The Editors and Publisher of Cancer Biology & Therapy wish to issue an Expression of Concern for the published article.
Jason Yongsheng Chan, Meng Seng Phoo, Marie-Veronique Clement, Shazib Pervaiz & Shao Chin Lee (2008) Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: The roles of caspase-6 and p53, Cancer Biology & Therapy, 7:8, 1305-1312, DOI: 10.4161/cbt.7.8.6302
Concerns have been raised that some bands in the western blot shown in Figure 4B appear to be very similar to one another.
In response to these concerns we contacted the corresponding author to clarify the situation and request the original files for us to assess the nature of these claims. The corresponding author responded to our queries, but explained the original data is not available due to the length of time that had elapsed between the experiments and the allegations being raised. The corresponding author has stated that none of the images presented in this article have been manipulated or duplicated. However, as the original data is not available for review, we cannot confirm that these western blot bands are not duplicates.
The Editors of Cancer Biology and Therapy would like to alert readers of this. We will provide an update if we receive any further information.