Article title: “Localization of PP2A-B56 to centromeres in Drosophila”
Authors: Emil Peter Thrane Hertz and Jakob Nilsson
Journal: Cell Cycle
Bibliometrics: Volume 16, Issue 15, pages 1385–1386
DOI: 10.1080/15384101.2017.1337986
The first paragraph of this article was mistakenly removed from the originally published version. The following paragraph should have been included.
Protection of chromosome cohesion through Shugoshin-dependent recruitment of the PP2A-B56 phosphatase to the pericentromeric region has become a cornerstone of the chromosome segregation model in eukaryotes. Shugoshin is essential for meiotic chromosome segregation in all tested eukaryotes but only found to be essential for mitotic chromosome segregation in vertebrates. Nishiyama and colleagues have now found that the protein Dalmatian, an ortholog of the vertebrate cohesion regulator Sororin, performs the function of Shugoshin in Drosophila melanogaster by recruiting PP2A-B56 to the pericentromeric region supporting an unified model of mitotic chromosome segregation in the animal kingdom. Here we speculate how Dalmatian might bind to PP2A-B56.
The online version of the article has been corrected.
The publisher apologizes for any inconvenience caused.