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Original Articles

Uric Acid Dye Inclusion Crystals

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Pages 187-193 | Published online: 31 Aug 2006
 

ABSTRACT

Crystallization in the presence of molecular dye probes has been used as a means of discerning surface recognition events that occur during the growth of uric acid (UA) and uric acid dihydrate (UAD), which are known components of some human kidney stones. The growth of synthetic UA and UAD crystals from supersaturated aqueous solutions containing seven different cationic dyes (Thionin, New Methylene Blue, Neutral Red, Acridine Yellow G, Safranine O, Bismarck Brown Y, and Bismarck Brown R) yielded dye-included crystals in all cases. Herein we describe the specific inclusion patterns and/or habit modification resulting from these growth conditions.

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