Synthesis, Characterization, Crystal Structure, and Hirshfeld Surface Analysis of 2–(2–Hydroxy–3–methoxyphenyl)–1–(4–methylphenyl)–4, 5–diphenyl–1H–imidazole

Abstract

The substituted imidazole C₂₉H₂₄N₂O₂ was prepared via multicomponent reactions and the product crystallized using dimethylformamide. The structure of the compound was established by elemental analysis, FT-IR, thermogravimetric analysis, UV-Visible, and single-crystal X-ray diffraction. The molecule is crystallized in the tetragonal crystal system with the space group P4₃2₁2 and with unit cell parameters a = 12.226(1) Å, b = 12.226(1) Å, c = 31.807(3) Å, and Z = 8. The molecular and crystal structure of the title molecule is stabilized by intramolecular interactions, O‒H···N and C‒H···N, and intermolecular interaction, C‒H···O.

Keywords:

• Crystallization
• crystal structure
• FTIR spectrum
• hirshfeld surface
• imidazole
• intermolecular interactions
• multicomponent reaction
• thermo gram

Acknowledgments

The authors thank the Institution of Excellence, Vigyana Bhavan, University of Mysore, Mysore, Karnataka, India, for providing single-crystal X-ray diffraction facility to collect the data. The author VS gratefully acknowledge the UGC and DST-PURSE for the financial assistance and Mangalore University, USIC and MICROTONE center for their instrumental facilities. NMR research center Bangalore for the NMR spectrum.