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Reviews

Lipases: From Production to Applications

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Pages 143-158 | Received 23 Jun 2017, Accepted 26 Nov 2018, Published online: 11 Jan 2019
 

Abstract

Lipases (triacylglycerol hydrolases E.C. 3.1.1.3) are enzymes produced by mammals, plants, fungi and bacteria that catalyze the hydrolysis of triacylglycerols into glycerol and fatty acids. Lipases are versatile in lipid biotechnology due to their selective properties, which have been applied in recent years in emulsifiers, pharmaceuticals, cosmetics, flavors, fragrances, as well as for the pretreatment of lipid-rich wastewater, the bioremediation of oils and biodiesel synthesis. This review offers information collected over the last 10 years on lipase sources as well as advances in production, purification strategies and the main applications in industry.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Additional information

Funding

The authors would like to thank the Brazilian National Council for Scientific and Technological Development (CNPq) under Grants (131725/2016-5 and 403893/2016-0), the Coordination for the Improvement of Higher Education Personnel (CAPES) under Grant (1776368) and Minas Gerais State Agency for Research and Development (FAPEMIG) under Grants (PPM-00129-16 and PPM-00644-18) for their financial support. The authors declare no conflict of interest.

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