Characterization of Crystallization Kinetics from Batch Experiments

ABSTRACT

This review outlines the techniques employed in experimental data reduction and analysis of batch crystallizers. A process description based on batch conservation equations describing population, mass and energy balances, both in crystal size and volume coordinate, together with appropriate kinetic events represented by phenomenological models and proper boundary conditions should be used in parameter identification. A number of general and useful techniques to extract growth and nucleation kinetics based on solution–side and solid–side information are reviewed. Procedures for parameter characterization for the phenomena of the growth rate dispersion and agglomeration are assessed.