Preparation and Characterization of Carboxymethyl-Functionalized Chitosan Fiber

Yingshan ZhouCollege of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of China;Key Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan, P.R. ChinaCorrespondence[email protected] [email protected]
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Longxian ShiCollege of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of ChinaView further author information

Fang LiCollege of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of ChinaView further author information

Hongjun YangCollege of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of China;Key Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan, P.R. ChinaView further author information

Xin LiuCollege of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of China;Key Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan, P.R. ChinaView further author information

Jun MaoHospital, Wuhan Textile University, Wuhan, P.R. ChinaView further author information

Weilin XuKey Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan, P.R. ChinaCorrespondence[email protected] [email protected]
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Abstract

Carboxymethyl chitosan fiber (CMCF) was successfully prepared and characterized by FTIR. The swelling behavior, mechanical property, antibacterial activity and indirect cytotoxicity assessment of CMCF were also studied, respectively. The results showed that, CMCF had higher liquid absorption capacity and lower tensile strength and elongation at break than those of chitosan fiber. The antibacterial activity of CMCF was similar with chitosan fiber, and carboxymethylation did not enhance the antibacterial activity directly. Indirect cytotoxicity assessment of the fibers indicated that CMCF was nontoxic to the L929 cell with relatively low extraction concentration. This novel fiber would be used as a potential wound dressing for skin regeneration.

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Funding

This work was financially supported by the Major State Basic Research Development Program (973 Program) (No. 2012CB722701) and National Natural Science Foundation of China (No.51203123).

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Preparation and Characterization of Carboxymethyl-Functionalized Chitosan Fiber

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Preparation and Characterization of Carboxymethyl-Functionalized Chitosan Fiber

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