In vitro assessment of antibacterial potential and mechanical properties of Ag-TiO₂/WPU on medical cotton optimized with response surface methodology

ABSTRACT

The environmental-friendly, economical, and simple one pot formulation for enhanced antibacterial and mechanical property finishing on medical cotton fabrics was successfully developed and optimized using a central composite design in conjunction with response surface methodology. It combines the concepts of in situ synthesis of AgNPs and photocatalytic property of TiO₂ in waterborne polyurethane as the finishing emulsion without additional organic reducing or stabilizing agent. The optimal formulation with contents of AgNO₃ (240 ppm) and TiO₂ NPs (980 ppm) exhibited excellent antibacterial activities against Klebsiella pneumoniae and Staphylococcus aureus with over 99% reduction and improved mechanical properties as well as non-toxicity to mammalian cells.

摘要

采用星点设计结合响应面法，成功地开发和优化了棉织物增强抗菌和机械性能整理的环保、经济、简便的一锅法。它结合的概念，在AgNPs和在水性聚氨酯TiO2的光催化性能的原位合成的整理乳液没有额外的有机还原或稳定剂。含AgNO₃的最佳配方（240 ppm）和TiO₂NPs（980 ppm）具有优异的抗菌活性，对肺炎克雷伯菌和金黄色葡萄球菌有超过99%的减少和改善的机械性能以及对哺乳动物细胞的非毒性。

KEYWORDS:

• Silver nanoparticles
• titanium dioxide
• waterborne polyurethane
• response surface methodology
• antibacterial activity
• cotton

关键词:

• 银纳米颗粒
• 钛白粉
• 水性聚氨酯
• 响应面法
• 抗菌活性
• 棉