Prevention of Postoperative Adhesion Bands by Alkali-treated Cellulosic Luffa Fibers

ABSTRACT

The formation of postsurgical intra-abdomen adhesion bands can cause severe complications. The luffa fibers were alkali treated to produce the desire hydrophobic and microfibrous structure. The scanning electron microscope and X-ray diffraction results have demonstrated that this treatment furnished a fine and hydrophobic fibrous structure. Moreover, the crystallinity of luffa increased from 17.4% to 63.32% by alkali treatment. Moreover, the in vivo results represented a significant reduction of inflammatory cells and adhesion bands after one week of luffa fibers implantation. These results suggest that the luffa fibers have the potential to act as a barrier for prevention of adhesion bands.

摘要

术后腹腔内粘连带的形成可导致严重的并发症.对丝瓜纤维进行碱处理，得到理想的疏水和微纤维结构.扫描电镜和X射线衍射结果表明，该处理具有良好的疏水性纤维结构.碱处理使丝瓜的结晶度由 17.4% 提高到 63.32%. 此外，体内实验结果显示，植入 luffa 纤维一周后，炎症细胞和粘附带明显减少.这些结果表明，丝瓜纤维有潜力作为一个屏障，防止粘附带.

KEYWORDS:

• Adhesion bands
• luffa
• fiber
• cellulose
• abdominal adhesion
• alkali treatment

关键词:

• 粘附带
• 纤维
• 纤维素
• 腹部粘连
• 碱处理

Acknowledgments

This work was financially supported by University of Nizwa Internal Grant and The Research Council Open Research Grant number 169. The authors gratefully acknowledge the technical support of Mr. Sayed Mohammed Farook.

Additional information

Funding

This work was supported by The Research Council [169].