Development of Secondary Layer of Wound Dressing Material Using Chitosan and Investigation for Hemostatic Efficiency

ABSTRACT

This study deals with effect of various concentrations of chitosan and material parameters on hemostatic properties of the woven and nonwoven dressings. The woven and nonwoven dressings are compared on efficacy on hemostasis. In addition to the studies on bio-polymer and minerals, 1% and 2% of chitosan particle dissolved solution were applied in both plain gauze and spunlace fabrics of cotton and viscose. The hemostatic efficacy and wound dressing suitability were analyzed and based on the results, the 2% chitosan viscose spunlace material was chosen due to its best performance for developing secondary layer for composite wound dressing.

摘要

本研究探讨了不同浓度的壳聚糖和材料参数对机织和非织造敷料止血性能的影响. 比较了机织和无纺布敷料的止血效果. 除了对生物聚合物和矿物质的研究外,还将1%和2%的壳聚糖颗粒溶解液应用于纯棉和粘胶的平纹纱布和水刺织物中. 对止血效果和伤口敷料的适用性进行了分析,并根据结果,选择了2%壳聚糖-粘胶水刺材料,因为其具有开发复合伤口敷料二次层的最佳性能.

KEYWORDS:

• Chitosan
• hemostatic efficacy
• plain gauze
• secondary layer
• spunlace
• wound dressing

关键词:

• 壳聚糖
• 止血效果
• 普通纱布
• 第二层
• 水刺
• 伤口敷料