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Journal of Dual Diagnosis
research and practice in substance abuse comorbidity
Volume 13, 2017 - Issue 1: Smoking and other CVD Risk Behaviors Among People with Mental Illness and/or Substance Use Disorders
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Antipsychotic Treatment and Tobacco Craving in People With Schizophrenia

Heidi J. WehringMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USACorrespondence[email protected]
, PharmD,
Stephen J. HeishmanNational Institute of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
, PhD,
Robert P. McMahonMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, PhD,
Fang LiuMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, MS,
Stephanie FeldmanMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, MSW,
Heather RaleyMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, MA,
Elaine WeinerMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, MD &
Deanna L. KellyMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
, PharmD show all
Pages 36-42 | Published online: 21 Mar 2017
 
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ABSTRACT

Objective: Nicotine dependence is high in schizophrenia, and craving is known to impact relapse during quit attempts. Methods: We compared tobacco craving in smokers with schizophrenia treated with different antipsychotics. Results: Mean craving scores were lowest in participants receiving first-generation antipsychotics, although these differences were not statistically significant. Craving with clozapine was not lower than with other antipsychotics. Conclusions: Further research is needed to determine whether differences in craving exist between antipsychotic classes.

Acknowledgment

We would like to thank the research participants for their involvement in this study.

Disclosures

There are no disclosures for any authors.

Funding

This study was funded in part by the National Institute on Drug Abuse (NIDA) Residential Research Services Contract HHSN271200599091CADB (N01DA-5-9909 Kelly, PI).

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