Liver Cirrhosis Due to Fetal CMV Infection: A Case Report

Abstract

Introduction: CMV is the most common cause of congenital viral infection. We observed a cirrhotic liver and intracerebral hemorrhage due to fetal CMV infection. Case presentation: Fetal CMV infection was diagnosed at 20 weeks of gestation, leading to termination of pregnancy. At fetopsy, the liver was macronodularly cirrhotic with necrosis and CMV inclusions. Intracerebral hemorrhage, seen on the prenatal ultrasound, was confirmed. Discussion/Conclusion: Congenital CMV infection can cause cirrhosis and intracerebral hemorrhage as early as 20 weeks gestation.

Keywords:

• Cirrhosis
• cytomegalovirus
• fetus
• liver
• pathology

Acknowledgement

None.

Statement of ethics

Written informed consent was obtained from the patient for publication of this case report and the accompanying images.

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding sources

The authors did not receive any funding sources

Author contributions

S.A.S., K.K.B.: conception, data acquisition, and interpretation, drafting of the work, final approval, and accountability agreement. S.A.: data acquisition and interpretation, revising it critically for important intellectual content, final approval, and accountability agreement. H.E.: drafting of the work, conception, data acquisition and interpretation, revising it critically for important intellectual content, final approval, and accountability agreement.