Cytogenetics of an Atypical Spitz Nevus Metastatic to a Single Lymph Node

Nicholas M. Smith Department of Paediatric Pathology, Royal Hospital for Sick Children, Edinburgh, United Kingdom

Margaret J. Evans Department of Paediatric Pathology, Royal Hospital for Sick Children, Edinburgh, United Kingdom

Andrew Pearce Lothian Area Cytogenetics Service, Royal Hospital for Sick Children, Edinburgh, United Kingdom

W. Hamish Department of Oncology, Royal Hospital for Sick Children, Edinburgh, United Kingdom

B. Wallace Department of Oncology, Royal Hospital for Sick Children, Edinburgh, United Kingdom

Abstract

Clinicopathologic details of an atypical Spitz nevus are reported. A metastasis to a single ipsilateral lymph node is documented. Cytogenetic analysis of the metastatic lesion revealed, a clonal chromosomal abnormality, add(6)(q12˜13), previously noted in cases of malignant melanoma.

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Cytogenetics of an Atypical Spitz Nevus Metastatic to a Single Lymph Node

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Cytogenetics of an Atypical Spitz Nevus Metastatic to a Single Lymph Node

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