Synthesis, Characterization, and DNA-Binding Studies of Lanthanide(III) Complexes Ln(H₂L) · (HL) · 0.5(bipy)·nH₂O¹

Abstract

A series of lanthanide(III) complexes Ln(H₂L) · (HL) · 0.5(bipy)·nH₂O (where Ln = Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Er, Yb, and H₃L = N-(2-propionic acid)-salicyloyl hydrazone, bipy = 2,2′-dipyridine) have been synthesized in ethanol-water mixture and characterized. The DNA-binding properties of these complexes were searched for the interaction with CT-DNA by electronic absorption titration and emission titration. The results showed that the interaction between Nd(III) complex and CT-DNA by surface/electrostatic binding, while all the other complexes can bind to calf-thymus DNA mainly by intercalation mode.

Keywords:

• DNA-binding
• hydrazone
• lanthanide(III) complexes

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Corrigendum

Acknowledgments

The work was supported by the important item 13115 of Shaanxi Province science and technology office (No. 08ZDKG-12), National Science Foundation of China (No. 30970308), and the National Science Foundation of China (No. 21273171).