Two quinazolinone-2-carboxylic acid copper(II) complexes synthesized by 4(3H)-quinazolinone-2-ethylformate high-temperature hydrolysis: Fluorescent and anticancer activity

ABSTRACT

Two novel copper(II) complexes of quinazolinone-2-carboxylic acid were synthesized by 4(3H)-quinazolinone-2-ethylformate high-temperature hydrolysis and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis, and solid-state fluorescence. Meanwhile, 1 was also tested for anticancer activity. By 4(3H)-quinazolinone-2-ethylformate high-temperature hydrolysis, we successfully avoided carboxyl decarboxylated, to synthesis of high-temperature easily decarboxylation complexes had a guiding role.

KEYWORDS:

• Complex
• quinazolinone-2-carboxylic acid
• synthesis
• hydrolysis

Funding

The authors acknowledge the financial support from the Guangxi Natural Science Foundation (No. 2014GXNSFAA118035), the Scientific Research and Technological Development Project of Guilin (NO.20110330), and the Guangxi Natural Science Foundation (No. 200807MS090), andGuangxi Zhuang Autonomous Region Department of Education Science Research Project (NO.YB2014331).