Synthetic and Biocidal Studies on The Complexes of 1-Aryl-2,5-dithiohydrazodicarbonamide with Co(II), Cu(II), and Zn(II)

Abstract

1-Aryl-2, 5-dithiohydrazodicarbonamide (aryl=ethoxyphenyl-(I) and chlorophenyl-(II)) forms 1:1 complexes of the type M(epthc) wherein M=Co(II), Ni(II), Cu(II) and Zn(II) and epthc=p-ethoxyphenyl dithiohydrazodicarbonamide; M(cpthc) M=Co(II), Cu(II) and Zn(II) and M(cpthc). 2H₂O (M=Ni(H)) and cpthc=p-chlorophenyldithiohydrazodicarbonamide. Magnetic and electronic spectral studies suggest tetrahedral geometry for Co(epthc) and Co(cpthc) while a square-planar geometry is indicated for Ni(epthc), Cu(epthc) and Cu(cpthc); Ni(cpthc). 2H₂O is shown to possess an octahedral geometry. Infrared spectra ascertain a binegative tetradentate behaviour of the ligands and the bonding sites are both hydrazidic nitrogens and the thiolo-sulphur. The Co(II), Ni(II) and Cu(II) complexes and ligands (I, II) have been found to exhibit pronounced antifungal activity against H. oryzae and A. flavus. The antibacterial properties of all the metal complexes and the ligands towards Bacillus-subtilis, Proteus microbilis and E. coli have been evaluated.