Cocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibiotics

Antonino Mazzone Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy

Leopoldo Giani Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy

Paola Faggioli Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy

Simona Pichini Drug Research and Evaluation Department, Istituto Superiore di Sanità, Roma, Italy

Roberta Pacifici Drug Research and Evaluation Department, Istituto Superiore di Sanità, Roma, Italy

Abstract

We describe a case of acute ischemia of the 2^nd, 3^rd and 4^th fingers of the right hand secondary to peripheral vascular occlusive disease induced by repeated intra-arterial cocaine injections. The complete occlusion of the distal arteries resolved following treatment with iloprost, a synthetic stable analogue of prostacyclin PGI2, in addition to anticoagulants and antibiotics.

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Cocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibiotics

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Cocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibiotics

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