Pemphigus herpetiformis-type drug reaction caused by erdosteine containing mucolytic in a child

Abstract

Drug-related pemphigus is very rare in children. Erdosteine is a thiol compound having mucoactive, antioxidant, anti-inflammatory, and antitussive effects and is reported to be safe for treatment of acute respiratory tract diseases in children. Herein, we report a 9-year-old boy presented with pemphigus herpetiformis associated with anti-desmoglein 1 antibodies due to erdosteine consumption.

Keywords:

• Autoimmune bullous disease
• cutaneous side effect
• thiol drug

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.