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Reviews

Recent Progress in the Biological Applications of Reactive Oxygen Species-Responsive Polymers

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Pages 114-143 | Received 28 Mar 2019, Accepted 02 Jul 2019, Published online: 23 Jul 2019
 

Abstract

Responsive polymeric materials that are sensitive to biological stimuli including temperature, pH, enzymes, or redox conditions have attracted research interest in recent years. Among these, reactive oxygen species (ROS)-responsive polymers are particularly appealing because of the special role of ROS in living organisms. ROS are the indicator and cause of certain diseases, and they are also important signaling molecules. ROS-responsive polymers could possess the following functions: drug carriers, ROS probes, or medications for certain ROS-related diseases. In this review, we analyze the progress about ROS-responsive polymers made in recent years and predict the future trends of ROS-responsive polymers from the above mentioned perspectives. Due to the limited scope of this review, some older articles are not covered here and are left for more comprehensive reviews.

Acknowledgement

We faithfully thank the National Basic Research Plan of China (2018YFA0208900), the National Science Foundation for Distinguished Young Scholars (Grant 21425416), the National Natural Science Foundation of China (Grant number 21734006) and the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (21821001) for their financial support. Also, we thank Yiheng Dai, who is currently a graduate student in our group, for his constructive suggestions.

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