http://orcid.org/0000-0002-9812-7573
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ABSTRACT
International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.
Acknowledgments
We would like to thank Charyl M. Dutton Gibbs and Lori R. Anderson for their expert secretarial assistance in the organization of the workshop. This meeting was supported by Mayo Clinic Center for Cell Signaling in Gastroenterology (C-SiG), GI Program of Mayo Clinic Comprehensive Cancer Center (MCCC), Basic Sciences Program of MCCC, Mayo Clinic SPORE in Pancreatic Cancer, Mayo Translational PKD Center (MTPC), Mayo Clinic Center for Biomedical Discovery (CBD) and Epigenomics Program of the Mayo Clinic Center for Individualized Medicine (CIM).
Disclosure statement
Nita Ahuja was an Advisor of Celgene and currently is in advisory board of Oncology Net Guide and Supporting Careers in Research for Interventional Physicians and Surgeons (SCRIPS) at Vanderbilt University School of Medicine. He also was consultant of Cepheid and Johnson & Johnson.