0
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

A Single Institution's 10 Year Experience of Treating High Grade Superficial Transitional Cell Carcinoma and Carcinoma In Situ of the Bladder with Intravesical BCG

, &
Pages 189-191 | Published online: 16 Jul 2015
 

Objective : The authors of this paper review the outcomes of patients at their institution who received intravesical Bacille Calmette-Guerin (BCG) for either high grade superficial TCC or CIS of the bladder over a 10-year period. Patients and methods : Seventy one patients received intravesical BCG over a 10-year period. Forty-one had primary CIS, 21 had G3 T1 disease and 6 had G3 Ta disease prior to commencement of BCG. The medical records of these patients were reviewed and the following details were recorded: time of diagnosis; time of commencement of BCG; result of the first check cystoscopy; time to first recurrence, if a recurrence occurred; time to disease progression, if this occurred; and cause of death if appropriate. Results : After a median follow up time of 22.5 months (range 6-114 months), 81% of the patients responded initially to BCG. During follow up 31% had a recurrence and 25% underwent disease progression. The mortality rate of the group as a whole from TCC was 16%. Conclusions : The authors feel that these results, which compare favourably with those previously reported, support the practice of using intravesical BCG in these high risk groups of patients, although these patients should be rigorously followed up and radical treatment should be considered should BCG "fail".

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.