An evaluation of alcohol sensitivity in the context of the acquired preparedness model

Abstract

Background: The acquired preparedness model (APM) posits that relationships between impulsivity-related traits and alcohol use are partly mediated by the biased acquisition of positive alcohol expectancies. Additionally, alcohol administration studies implicate associations between impulsivity-related traits and sensitivity to acute alcohol effects, suggesting that impulsivity-expectancy associations could be partly explained by individual differences in alcohol response. The present study assessed a theoretical extension of the APM by testing the prediction that self-reported sensitivity to alcohol would partly mediate impulsivity-expectancy relationships, and that the addition of alcohol sensitivity variables would account for increased variance in drinking quantity and problems relative to the traditional APM.

Method: Young adult heavy drinkers (N = 300, 53% women) completed the Alcohol Sensitivity Questionnaire, the UPPS-P Impulsive Behavior Scale, and measures of alcohol expectancies (Comprehensive Effects of Alcohol Questionnaire) and drinking quantity and related problems. Hypotheses were examined using path analysis.

Results: Results supported significant indirect effects of sensation seeking on drinking quantity and problems via higher positive expectancies. Results also supported a significant indirect effect of negative urgency on drinking problems via negative expectancies. Although alcohol sensitivity variables showed unique associations with drinking outcomes, the addition of these variables did not improve model fit and hypothesized indirect paths involving impulsivity-related traits, alcohol sensitivity, and expectancies were not supported.

Conclusions: Future research is necessary to reconcile these results with laboratory findings suggesting that impulsive traits are frequently associated with sensitivity to alcohol’s acute effects.

Keywords:

• Alcohol response
• acquired preparedness
• impulsivity
• expectancy
• personality

Additional information

Funding

This work was supported by the Canadian Institutes of Health Research under Grants MOP-119444 and MSH-130189; the Ontario Mental Health Foundation; ABMRF/The Foundation for Alcohol Research; NIH R21AA020304, and the Canada Research Chairs program.