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Research Article

Microwave induced synthesis of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters and their antibacterial activity

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Pages 347-351 | Received 17 Nov 2005, Published online: 01 Feb 2007
 

Abstract

A series of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters, (3a–i) have been synthesized by the condensation of 2-chloro-3-formyl quinolines (1a–c) with thioglycolic acid/alkyl esters under microwave irradiation using anhydrous potassium carbonate. These compounds were characterized by elemental analysis, IR, 1H NMR, and mass spectral studies. Their antibacterial activity was also evaluated.

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