Abstract
A series of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters, (3a–i) have been synthesized by the condensation of 2-chloro-3-formyl quinolines (1a–c) with thioglycolic acid/alkyl esters under microwave irradiation using anhydrous potassium carbonate. These compounds were characterized by elemental analysis, IR, 1H NMR, and mass spectral studies. Their antibacterial activity was also evaluated.