Rapid and efficient synthesis of sulfonamides from sulfonic acid and amines using cyanuric chloride-DMF adduct

Abstract

A one-pot procedure that has been developed for the rapid and efficient synthesis of sulfonamides from sulfonic acids and amines using cyanuric chloride (2,4,6-trichloro-1, 3,5-triazine, TCT, CyCl) and N,N-dimethyl formamide at room temperature has been described.

Keywords:

• sulfonamides
• sulfonic acids
• amines
• cyanuric chloride

Acknowledgements

SSP thanks UGC New Delhi, for a teacher fellowship under the FIP scheme.