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Journal of Sulfur Chemistry Volume 29, 2008 - Issue 6
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Research Articles

Synthesis of 2,5-diaroyl-3-arylthiophenes: novel tandem reactions mediated 3+2-self annulation of bis(aroylmethyl) sulfides

Gurusamy Ravindran School of Chemistry, Madurai Kamaraj University, Madurai, India
,
Nidhin Paul School of Chemistry, Madurai Kamaraj University, Madurai, India
,
Shanmugam Muthusubramanian School of Chemistry, Madurai Kamaraj University, Madurai, IndiaCorrespondence[email protected]
&
Subbu Perumal School of Chemistry, Madurai Kamaraj University, Madurai, India
Pages 575-581 | Received 30 Apr 2008, Published online: 22 Nov 2008
 
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Abstract

A series of 2,5-diaroyl-3-arylthiophenes were obtained from the 3+2-self annulation of bis(aroylmethyl) sulfides in the presence of sodium hydroxide. This transformation occurs presumably via a tandem intermolecular condensation - ring closing intramolecular displacement-aromatization via air oxidation and elimination sequence.

Acknowledgements

The authors thank DST, New Delhi for their assistance under the IRHPA program for the nuclear magnetic resonance facility. One of the authors (NP) thanks UGC, New Delhi for a research fellowship.

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