Abstract
Electrogenerated magnesium-associated cyanomethyl anions/bases obtained from the electrochemical reduction of acetonitrile and the oxidation of a sacrificial magnesium rod were successfully used to promote the addition of carbon disulfide to primary benzylic amines. Alkylation with ethyl 3-bromopropionate acid ester or with ethyl 2-bromoacetate acid ester yields the corresponding ring-opened carbamodithioate compounds or cyclic rhodanine derivatives, respectively. The effect of the amount of electrogenerated base on the yield of reaction was also evaluated.
Acknowledgements
The authors gratefully acknowledge the Tunisian “Ministère de l'Enseignement Supérieure, de la Recherche et la Technologie” for financial support (Lab CH-02). Bernd Schöllhorn is acknowledged for his valuable help during the preparation of the manuscript.