![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
ABSTRACT
A novel, simple and efficient synthetic protocol has been developed for the synthesis of a series of thiazolidine-4-one and 3H-thiazole derivatives via a one-pot four-component condensation-cyclization reaction of hydrazine with allyl isothiocyanate and an α-haloketone in the presence of various aldehydes. This new protocol produces novel thiazolidine-4-one and 3H-thiazole derivatives in excellent yields. The remarkable features of this methodology are high yields, easy work-up and a one-pot simple reaction method.
GRAPHICAL ABSTRACT
Disclosure statement
No potential conflict of interest was reported by the authors.
Acknowledgements
The authors gratefully acknowledge support by the Institute for Advanced Studies in Basic Sciences (IASBS) Research Council.
Additional information
Funding
This work was supported by Iran National Science Foundation (INSF) major project (Grant No. 93048780) and Postdoc programs of Institute Advanced Studies Basic Science-Zanjan (Iran).
