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Articles

High yielding protocol for direct conversion of thiols to sulfonyl chlorides and sulfonamides

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Pages 256-264 | Received 04 Aug 2018, Accepted 08 Jan 2019, Published online: 30 Jan 2019
 

ABSTRACT

In this paper, a new method for oxidative chlorination of thiols to sulfonyl chlorides and sulfonamides using H2O2 in the presence of TMSCl is reported. The excellent yields, short reaction times, excellent efficiencies, low costs, and easy separation of products are the most important advantages of this method.

GRAPHICAL ABSTRACT

Disclosure statement

No potential conflict of interest was reported by the authors.

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