Morphological and antibacterial effects of silver, magnesium, silicon and strontium modified calcium phosphate bone cements prepared by the sol–gel method

ABSTRACT

In this study, the sol–gel method was used to add MgO and SrBr₂ to biografts containing Ca(NO₃)₂·4H₂O, SiO₂, P₂O₅, H₃BO₃ and AgNO₃. In addition, urea (15–35% by weight) was added to these biografts in different ratios. FTIR, XRD and SEM–EDX analyses were performed in order to observe the morphological effects. Antibacterial tests were carried out using S.aureus and E.coli bacteria. As a result of FTIR analysis, it was observed that H–OH, CO³⁻, ${\mathrm{CO}}_3^{3-}$, ${\mathrm{PO}}_4^{3-}$, Si–O and Si–O–Si compound structures were formed in the biografts. XRD analysis was found that HA (Hydroxyapatite), β-TCP, CaSiO₃, CaMgSi₂O₆, Ca₃MgSi₂O₈, CaMgSi₂O₆ and Mg₁₇Sr₂ compound structures were formed. Antibacterial analysis with E. coli showed that all biografts except the one that contained the highest amount of urea (35% by weight) yielded colony counting values close to the negative control. For S. aureus, the opposite result was observed.

KEYWORDS:

• Bone grafts
• SrBr₂
• AgNO₃
• antibacterial effects

Disclosure statement

No potential conflict of interest was reported by the author(s).