Predicting long-term graft survival after keratoplasty

ABSTRACT

Introduction: Significant progress has been made in the field of corneal transplantation over the last 15 years, and a progressively more targeted approach to the surgical treatment of the various corneal conditions is being adopted. These newer techniques promise less complications and improved outcomes.

Areas covered: In this review, the authors summarize the various large randomized clinical trials and observational studies that have been performed to evaluate these procedures and identify the factors predicting the best outcomes.

Expert commentary: Continued follow-up and reporting of long-term data from large prospective multi-center studies, as well as new studies evaluating and comparing the newer surgical techniques, will be invaluable in predicting and optimizing the long-term outcomes of these procedures.

KEYWORDS:

• Penetrating keratoplasty
• deep anterior lamellar keratoplasty
• Descemet stripping endothelial keratoplasty
• Descemet membrane endothelial keratoplasty
• endothelium
• Fuchs’ dystrophy
• pseudophakic/aphakic corneal edema

Declaration of interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Additional information

Funding

No funding to declare.