Declaration of interest
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
Reviewer disclosures
A reviewer of this manuscript discloses receiving funds from Sanofi and Alexion. A separate reviewer discloses being a principal investigator and one of the authors of the manuscript on the HERCULES trial. Peer reviewers on this manuscript have no other relevant financial or other relationships to disclose.