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RESEARCH LETTERS

Synthesis of β-amino alcohols by ring opening of epoxides with amines catalyzed by cyanuric chloride under mild and solvent-free conditions

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Pages 275-281 | Received 08 Sep 2009, Published online: 08 Dec 2010
 

Abstract

The 2,4,6-trichloro-1,3,5-triazine catalyzed synthesis of β-amino alcohols by aminolysis of epoxide under solvent-free condition is described. Mild reaction conditions, short reaction times, inexpensive and readily available catalysts, and excellent yields of the products with high regioselectivity are attractive features of this methodology.

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