An efficient green protocol for the synthesis of chalcones by a Claisen–Schmidt reaction using bismuth(III)chloride as a catalyst under solvent-free condition

Abstract

An environmentally benign protocol for the synthesis of chalcones by the Claisen–Schmidt condensation of aldehydes with ketones using eco-friendly non-toxic bismuth(III)chloride catalyst under solvent-free condition is reported. In this protocol, the reaction time is very short, yields are high, and there are no other pollutants formed.

Keywords:

• aldehydes
• ketones
• Claisen–Schmidt condensation
• bismuth(III)chloride
• chalcones
• solvent free

Acknowledgements

The authors are thankful to the Council of Scientific and Industrial Research, New Delhi, India, for financial assistance and to the Indian National Science Academy, New Delhi, India, for additional financial support for this research project.