![Sample our Health and Social Care journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5938/TOC-Subject-Sample-2021-Health-Social-Care.jpg"})
Abstract
Trihexyphenidyl is prone for abuse as well as dependence and produces a characteristic withdrawal syndrome. We present the case history of a 55-year-old lady who had an apparent worsening of her psychosis when trihexyphenidyl was withdrawn, and the dramatic resolution of her symptoms once it was re-introduced. Clinicians should consider such a presentation in patients with psychosis who are otherwise well maintained on antipsychotics. In view of the above as well as the known cognitive side effects of anticholinergic medications, long-term use of these agents should be avoided unless clearly indicated.