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Invited Articles

Understanding, facilitating and predicting aphasia recovery after rehabilitation

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Abstract

Purpose: This paper reviews several studies whose aim was to understand the nature of language recovery in chronic aphasia and identify predictors of how people may recover their language functions after a brain injury.

Method: Several studies that mostly draw from data collected within the Centre for Neurobiology of Language Recovery were reviewed and categorised in four aspects of language impairment and recovery in aphasia: (a) neural markers for language impairment and recovery, (b) language and cognitive markers for language impairment and recovery, (c) effective treatments and (d) predictive modelling of treatment-induced rehabilitation.

Result: Language impairment and recovery in stroke-induced aphasia is multi-factorial, including patient-specific and treatment-specific factors. A combination of these factors may help us predict treatment responsiveness even before treatment begins.

Conclusion: Continued work on this topic will lead to a better understanding of the mechanisms that underly language impairment and treatment-induced recovery in aphasia, and, consequently, use this information to predict each person's recovery profile trajectory and provide optimal prescriptions regarding the type and dosage of treatment.

Disclosure statement

M. Varkanitsa reports there are no competing interests to declare. S. Kiran is a scientific advisor for Constant Therapy Health.

Additional information

Funding

The work reviewed in this paper was funded by the NIH/NIDCD [under Grant Nos. 1R01DC016950; 1U01DC014922; 1P50DC012283] and Boston University Digital Health Initiative.

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