Publication Cover
Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 28, 1973 - Issue 1
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Original Articles

Effet Favorable Du Trimethoprim-Sulfamide (Eusaprim) Dans Un Cas De Rectocolite Hemorragique

Pages 17-19 | Published online: 19 May 2016
 

Summary

A 36 years-old man, suffering since more than ten years from a severe hemorrhagic recto-colitis (ulcerative colitis) experienced a bad relapse at the beginning of 1972. Treatment with Salazopyrin (Azulfidin) and ACTH proved of no avail. Because of a white cell count of 14,200 it was decided to resort to an anti-infectious therapy : Trimethoprim-sulfamide (Eusaprim) was given in daily amounts of 4 tablets for one week ; afterwards the daily dose was reduced to 2 tablets. Results were spectacular : within three days the diarrhea ceased ant there occurred only a minimal passage of blood after bowel movements. The left colon was no longer tender. Within the next five months the body-weight increased with 6 Kg.

Samenvatting

Bij een 36-jarige patiënt die reeds meer dan tien jaar aan een hemorragische rectocolitis leed, werd, tijdens een hervalperiode die weerstandig bleek aan Salazopyrine en ACTH, een uitstekende uitslag op enkele dagen bekomen na toediening van trimethoprim-sulfamide (Eusaprim). De dagelijkse dosis bedroeg 4 tabletten gedurende een week ; daarna, 2 tabletten. Op vijf maanden tijd vermeerderde het lichaamsgewicht met 6 Kg.

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