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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 79, 2024 - Issue 2
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Research Article

Belgian 2024 guidance on the use of pre-exposure prophylaxis

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Pages 121-129 | Received 16 Feb 2024, Accepted 12 May 2024, Published online: 22 May 2024
 

ABSTRACT

Objectives

We aimed to develop a guidance on the use of pre-exposure prophylaxis (PrEP) for HIV tailored to the Belgian context.

Methods

Different aspects of PrEP care were judged by an expert group of nine Belgian clinicians, seeking consensus for areas of controversies.

Results

PrEP should be considered in HIV negative patients at high risk of acquiring HIV. Currently, only oral tenofovir/emtricitabine is available in Belgium for PrEP, which can be used daily, or also event-driven in cisgender men and trans women who are not taking exogenous estradiol-based hormones. Personal counselling directed at medication adherence and sexual health should have a central role in PrEP care. At the initial assessment clinicians should give attention to symptoms of an acute HIV infection, the patients’ immunization status and renal function. A regular follow-up must be set up to diagnose HIV seroconversion, treat sexually transmitted infections, and manage side effects of PrEP.

Conclusion

The Belgian guidance on the use of PrEP provides a point of reference for standard PrEP care in Belgium and will be periodically updated.

Acknowledgments

The authors would like to thank Dirk Avonts, Vincent Barvaux, Rémy Demeester, Pierre-Louis Deudon and Marie-Angélique De Scheerder for critical reading of the manuscript.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/17843286.2024.2356337

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