Disappearance of Epileptic Bursts on Rat Hippocampal Slices by Using Laser Irradiation

Yuya Hirayama Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyusyu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu-shi, Fukuoka, 808-0196, Japan

Satoru Ishizuka Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyusyu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu-shi, Fukuoka, 808-0196, Japan

Zimin Lev Grigorievich Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyusyu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu-shi, Fukuoka, 808-0196, Japan

Takeshi Yamakawa Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyusyu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu-shi, Fukuoka, 808-0196, Japan; Fuzzy Logic Systems Institute, 680-41 Kawazu, Iizuka, Fukuoka, 820-0067, Japan

Abstract

Laser irradiation is applied to some medical treatments such as dentistry, dermatology, cancer and is also expected to a brain surgical treatment. However, the effect of laser irradiation on brain nerves is not well known. We examined the influence of semiconductor pulse laser irradiation on epileptic bursts in the CA3 region of rat hppocampal slices in the experiment. Epileptic bursts were eliminated on the CA3 by the laser light of energy over 20.0 mJ/cmZ, and the effect was confined to the irradiation area. These results show that the laser irradiation has a possibility for an epilepsy surgical treatment.

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Disappearance of Epileptic Bursts on Rat Hippocampal Slices by Using Laser Irradiation

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Disappearance of Epileptic Bursts on Rat Hippocampal Slices by Using Laser Irradiation

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