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Abstract
The realization of minimally invasive epilepsy surgery treatment, our goal, needs the excision of the focus accurately by minimally invasive way. We think one of the best ways is cryosurgery. However, cryosurgery is not applied to epilepsy and the effect of cryosurgery on brain tissue is not well known. In this paper, we investigated the effectivity of cryosurgery by application to rat brains. We performed cryosurgery to rat under the several conditions. After these surgeries, we stained these specimens with H&E and observed them about changes in the tissue. These results shows cryosurgery can be applied to epilepsy.