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Abstract
Human immunodeficiency virus (HIV) infection, first described in gay men over 30 years ago, remains an important medical issue to the lesbian, gay, bisexual, and transgender (LGBT) community. While HIV infection is an issue globally and nationally among all populations, in the United States, gay and bisexual men and male-to-female (MTF) transgender people are disproportionately affected. This article intends to serve as an update on the medical aspects of HIV care for the nonspecialist, including epidemiology, diagnosis, treatment, and prevention, with a focus on what is currently known about these aspects of HIV with respect to LGBT populations.