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ABSTRACT
In this study, we examined the effect of doxycycline hydrochloride (DH) on apical seal. Results indicated that teeth that were retrofilled with IRM or amalgam following doxycycline irrigation had significantly less dye penetration (p<0.05). Due to its antimicrobial activity, smear layer removal ability, and improvement of apical seal, doxycycline solution may be used as an irrigant.
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Notes on contributors
Rahmat A. Barkhordar
Rahmat A. Barkhordar, DMD is an associate professor in the Department of Restorative Dentistry at the University of California, San Francisco.
Thomas Russel
Thomas Russel, DMD, is a clinical assistant professor in the Department of Restorative Dentistry at the University of California, San Francisco.