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Case Reports

An unusual case of chronic lymphocytic leukemia, multiple myeloma and cardiac amyloidosis

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Pages 230-233 | Received 06 Apr 2017, Accepted 07 Aug 2017, Published online: 19 Sep 2017
 

ABSTRACT

Light chain amyloidosis has very rarely been reported in association with chronic lymphocytic leukemia (CLL). We reported on a 76-years-old female who presented with simultaneous kappa-restricted chronic lymphocytic leukemia (CLL) and a lambda-restricted multiple myeloma with plasma cells causing AL amyloidosis involving the heart. While monoclonal immunoglobulins occasionallyproduced by CLL have previously been implicated in AL amyloidosis, there only a few cases reported of AL amyloidosis resulting from a distinct plasma cell dyscrasia that is not clonally related to the concurrent CLL.

Disclosure statement

No potential conflict of interest was reported by the authors.