HIF-1 is a critical target of pancreatic cancer: OncoImmunology: Vol 4, No 9

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Abstract

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal digestive tract malignancies. Hypoxia-inducible factor (HIF-1) is over-expressed in pancreatic cancer and associated with poor prognosis. During the past several years, we focused on identifying the function of HIF-1 and the antitumor effect of HIF-1 inhibitors on PDAC, especially in regards to immunogenic cell death.

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No potential conflicts of interest were disclosed.

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HIF-1 is a critical target of pancreatic cancer

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HIF-1 is a critical target of pancreatic cancer

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