Practical review of immunizations in adult patients with cancer

Abstract

Compared with the general population, patients with cancer in general are more susceptible to vaccine-preventable infections, either by an increased risk due to the malignancy itself or immunosuppressive treatment. The goal of immunizations in these patients is therefore to provide protection against these infections, and to decrease the number of vulnerable patients who can disseminate these organisms. The proper timing of immunization with cancer treatment is key to achieving better vaccine protection. As the oncology field continues to advance, leading to better quality of life and longer survival, immunization and other aspects of preventive medicine ought to move to the frontline in the care of these patients. Herein, we review the vaccines most clinically relevant to patients with cancer, as well as special cases including vaccines after splenectomy, travel immunization and recommendations for family members.

Keywords:

• cancer
• immunization
• infection
• prevention
• vaccine

Disclosure of Potential Conflicts of Interest

R.F.C. has received research funding from GlaxoSmithKline. E.J. A-H. declares no conflict of interest.

Acknowledgments

We thank Mr. Joseph Munch, Scientific publications, for his editorial revision of the article.