Mumps virus pathogenesis: Insights and knowledge gaps

Sigrid GoumaCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands;Department of Viroscience, Erasmus University Medical Centre, Rotterdam, The NetherlandsCorrespondence[email protected]

Marion P. G. KoopmansCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands;Department of Viroscience, Erasmus University Medical Centre, Rotterdam, The Netherlands

Rob S. van BinnendijkCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

ABSTRACT

The recent mumps outbreaks among MMR vaccinated persons have raised questions about the biological mechanisms related to mumps symptoms and complications in the background of waning immunity. Contrary to other paramyxoviruses, the understanding of mumps virus pathogenesis is limited, and further in-depth clinical studies are required to provide answers to important research questions.

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No potential conflicts of interest were disclosed.

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Mumps virus pathogenesis: Insights and knowledge gaps

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Mumps virus pathogenesis: Insights and knowledge gaps

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