May rotavirus vaccine be affect food allergy prevalence?

ABSTRACT

Incidence of food allergy (FA) during nursing period is 6–8% globally and It is reported %5,7 in Turkey. In our study, the aim is to determine whether the prevalence of food allergy (FA) increases in children vaccinated against rotavirus. The files of 681 infants who are still followed-up were retrospectively evaluated. Children who did not come to our clinic for all of their well-child follow-up visits were excluded from the study. Moreover, children diagnosed with allergy before vaccination and children with known gastrointestinal system disease were excluded from the study. The number of patients diagnosed with food allergy after being vaccinated against rotavirus was 12 (1.76%). Three children had a family history of allergy. Of 12 patients who were diagnosed after vaccination, 3 (n:104) were vaccinated with pentavalent vaccine and 9 (n:507) with monovalent vaccine. In the monovalent vaccination group, food allergy was found in 9 children (1.55%), and in the pentavalent vaccination group, food allergy was found in 3 children (2.88%). The difference between the two vaccination groups in terms of food allergy prevalence was not significant (p > .05). Although it is believed that food allergy, and even cow’s milk protein allergy (CMPA) prevalence increases in infants vaccinated against rotavirus, in this study, no significant increase was observed in the prevalence of food allergy after rotavirus vaccination. Both types of vaccine had similar rates to each other.

KEYWORDS:

• Allergy
• cow milk
• food
• rotavirus
• vaccine

Abbreviation

Table

Author contribution

Conceptualization NMK and OYO, Methodology NMK and OYO, Formal analysis NMK and OYO, Data curation NMK, AS, EA, IA, ZIB, and SC, writing NMK, review NMK, BTK, and OYO. All authors read and approved the final manuscript.

Disclosure of potential conflicts of interest

The authors report no conflict of interest.

Ethical approval

This study was conducted according to the guidelines laid down in the Declaration of Helsinki and all procedures involving research study participants were approved by the University Institutional Review and Ethical Board (Project No: KA18/99).

Additional information

Funding

There is no funding source.