ABSTRACT
Vaccination is the most cost-effective way to prevent mothers and infants from contracting tetanus. However, developing countries struggle with the persistent low take-up of vaccination. The low risk perceptions of disease can be one of the barriers to vaccination. One way to increase the risk perceptions of disease is to use salient loss-framed messages to highlight negative consequences of not getting vaccinated. We conducted a randomized controlled trial among 1,660 women in 80 villages in northeastern Nigeria. Respondents were randomly assigned to view one of two flipcharts: (1) control flipcharts, which contained written explanation about the severity of the disease, or (2) `scared-straight’ flipcharts that contain the salient information about the disease severity in addition to the written explanation about the severity of the disease. Additionally, respondents were provided randomly assigned amounts of cash incentives. The scared-straight intervention backfired among women with no previous experience of tetanus vaccination: it decreased their vaccine take-up by 3.7–6.1 percentage points, even though it increased their perceived risk of disease and their fear level. The negative effect of the scared-straight intervention is the most prevalent among women who received the lowest amount of cash incentive. Women without experience of tetanus vaccination might have responded to the scared-straight flipcharts by denying the information provided because the flipcharts were too frightening. The use of the scared-straight tactic is not recommended to aim for the improved take-up of vaccination in developing countries where people might face budget constraints for achieving desirable behaviors.
Trial Registration: The trial was registered at ISRCTN registry (ID: ISRCTN95083356).
Acknowledgments
We are grateful to Abdullahi Belel and the Adamawa State Primary Health Care Development Agency for their cooperation and support throughout the project implementation. We give special thanks to Benjamin Fintan and the field team who devoted themselves to the project. This project was supported with research grants from the Japan Society for the Promotion of Science.
Disclosure of potential conflicts of interest
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Ethics approval
Ethics approval was obtained on November 2012 from University of Michigan Health Sciences and Behavioral Sciences Institutional Review Board (HUM00063832). Oral and written informed consents were obtained from all the respondents prior to their participation in the study.
SUPPLEMENTARY MATERIAL
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