ABSTRACT
The article by Abdalla et al., published in the journal on 28 May 2021, raised a concern. The SARS-CoV-2 spike (S) protein is the major targeted surface glycoprotein in COVID-19 vaccines. Many mutations in the S protein of SARS-CoV-2 have been reported across the globe. The S protein plays a crucial role in the induction of neutralizing antibody and protective immunity against SARS-CoV-2 infection. The protein biochemistry and immunology, in addition to conventional virology, will help us to delineate the biology of SARS-CoV-2 variants.
Acknowledgments
We thank Dr Monika Koul for proofreading the text and Abhay Singh for excellent technical support. The virus research in our laboratory is currently supported by the Department of Biotechnology, India (BT/PR24308/NER/95/644/2017 and BT/PR41246/NER/95/1685/2020) and the Department of Health Research, Government of India (NER/71/2020-ECD-I).
Disclosure of potential conflicts of interest
No potential conflicts of interest were disclosed.