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Public Health & Policy

Immunity to measles in COVID-19 era

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The letter to the Editor “Measles vaccine uptake and COVID-19”Citation1 commenting on our recent paper “Measles vaccine uptake among Italian medical students compared to the pre-COVID-19 era”Citation2 raises concerns about some potential limitations of our findings. The authors comment that the retrospective-based approach used in the study may have introduced limitations such as constraints on data accuracy, completeness, and potential bias. In addition, the applicability of our findings to other settings or health care areas would be limited because only one teaching hospital was included in the study.

First, we would like to emphasize that the study is based on data from reliable sources, such as personal information, laboratory results and official vaccination records, which were previously collected by the Occupational Health Department through a rigorous verification process, in accordance with Italian law. Therefore, it is unlikely that the data collection methodology could have led to inaccuracies or misleading results.

Second, although conducted in a single university hospital, our study included a relatively large sample of medical students, and indeed our findings are consistent with those of similar studies from different EU and non-EU countries.Citation3,Citation4 In the current epidemiological picture, vaccination policy in response to changing epidemiology is a critical component of public health. According to a recent paper evaluating measles status and vaccine policy development in six European countries, mandatory vaccination has effectively increased childhood measles vaccination coverage in Italy, and similar benefits could be expected from vaccine mandates in other countries.Citation5

Vaccine hesitancy among healthcare workers remains a major public health issue; interventions targeting future medical operators and addressing student vaccine hesitancy and knowledge gaps are critical.

Author’s contribution

Cristiana Ferrari was involved in revising the paper critically for intellectual content and the final approval of the version to be published; Giuseppina Somma was involved in drafting of the paper and revising it critically for intellectual content; Luca Coppeta was involved in conception and design and drafting of the paper. All authors agree to be accountable for all aspects of the work.

References

  • Daungsupawong H, Wiwanitkit V Measles vaccine uptake and COVID-19. Hum Vaccin Immunother. 2023 Aug;19(2):2261195. Epub 2023 Sep 19. PMID: 37725096; PMCID: PMC10521584. doi:10.1080/21645515.2023.2261195.
  • Ferrari C, Somma G, Olesen O, Buonomo E, Pasanisi Zingarello M, Mazza A, Rizza S, Di Giampaolo L, Magrini A, Ponzani F, et al. Measles vaccine uptake among Italian medical students compared to the pre-COVID-19 era. Hum Vaccin Immunother. 2023;19(2):2252681. doi:10.1080/21645515.2023.2252681.
  • Bertoncello C, Nicolli A, Maso S, Fonzo M, Crivellaro M, Mason P, Trevisan A. Uptake of non-mandatory vaccinations in future physicians in Italy. Vaccines (Basel). 2021 Sep 17;9(9):1035. PMID: 34579272; PMCID: PMC8473324. doi:10.3390/vaccines9091035.
  • Freund R, Krivine A, Prévost V, Cantin D, Aslangul E, Avril MF, Claessens YE, Rozenberg F, Casetta A, Baixench MT, et al. Measles immunity and measles vaccine acceptance among healthcare workers in Paris, France. J Hosp Infect. 2013 May;84(1):38–1. Epub 2013 Feb 20. PMID: 23433868. doi:10.1016/j.jhin.2013.01.002.
  • Vojtek I, Larson H, Plotkin S, Van Damme P. Evolving measles status and immunization policy development in six European countries. Hum Vaccin Immunother. 2022 Dec 31;18(1):2031776. Epub 2022 Feb 18. PMID: 35180372; PMCID: PMC9009904. doi:10.1080/21645515.2022.2031776.