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Original Articles

Integrated bioinformatics analysis of miRNA expression in osteosarcoma

, , &
Pages 936-943 | Received 23 Apr 2016, Accepted 28 May 2016, Published online: 17 Jun 2016
 

Abstract

The expression of miRNA influencing the pathogenesis of OS have been reported previously, however, different samples selection and sequencing platforms made obvious differences in miRNA expression analysis. We aim to identify reliable prognostic and treatment biomarkers for OS by systematic analysis of miRNAs expression data sets from biased data set. Seven miRNA data sets were selected from corresponding articles. Collectively, two miRNAs, hsa-miR-19-3p and hsa-miR106b-3p, and transcription factor SIX3 were identified and may be reliable markers for prognostic and treatment of osteosarcoma.

Disclosure statement

All authors declared no conflict of interest.

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